1481 year. You play as a young John, who is publicly humiliated and lives down the street. On suspicion of witchcraft, he is tortured in the prison of the Spanish Inquisition. Later, he experiences an alchemical transformation that makes him immortal. But not everything goes according to plan. After each resurrection, John completely loses his memory. 500 years later, now, John lives in Paris with Pauline, his immortal wife. Together they are looking for an artifact, which is necessary for the reproduction of the ritual.